Antileukemic activity of the HSP70 inhibitor pifithrin-μ in acute leukemia
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چکیده
منابع مشابه
Antileukemic activity of the HSP70 inhibitor pifithrin-μ in acute leukemia
Heat shock protein (HSP) 70 is aberrantly expressed in different malignancies and has emerged as a promising new target for anticancer therapy. Here, we analyzed the in vitro antileukemic effects of pifithrin-μ (PFT-μ), an inhibitor of inducible HSP70, in acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL) cell lines, as well as in primary AML blasts. PFT-μ significantly inhibit...
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ژورنال
عنوان ژورنال: Blood Cancer Journal
سال: 2011
ISSN: 2044-5385
DOI: 10.1038/bcj.2011.28